The idea is to evaluate if the so called "Gluten Sensitivity" is a real clinical entity. Gluten sensitive (GS) persons are defined as those patients, being neither celiac or allergic to weat, who develop symptoms following gluten consumption.
A comprehensive listing of clinical trials (both government and industry sponsored) conducted across the U.S. Use key terms "celiac disease" or" gluten sensitivity".
The Beyond Celiac Clinical Trials Resource Center
Beyond Celiac Clinical Trials Resource Center, presented in partnership with CenterWatch, the leading publisher of information on clinical research for patients and their advocates and healthcare professionals.
Celiac Disease Drug Development in the News
Read updates from the research field, including calls for enrollment in clinical trials, results from previous celiac disease trials, and advances in funding for continued research.
Larazotide acetate, (Alba Therapuetics) is a drug currently in development that works by inhibiting zonulin, which has been shown to increase the permeability of the gut in celiac disease, allowing gluten particles to pass through to trigger inflammation, and gastrointestinal and other symptoms. Larazotide acetate is a novel agent that belongs to a new class of drugs called tight junction regulators. It is a synthetic eight amino acid peptide that has the sequence GGVLVQPG.
Gluten is a protein found in wheat. What part of the wheat grain is it located? How can you identify foods that contain gluten? ... read more.What are the genes in the Human Genome responsible for Celiac Disease?
There are two genes that are responsible for Celiac disease although other genes and environmental factors play a role in those that get the disease, since as many as 30-40% of the population may have the gene(s) but not show symptoms... read more.Why is an immune response triggered against gluten in some individuals?
How does gluten cause celiac disease?... read moreWhat is the difference between celiac disease and gluten sensitivity?
Only 1% percent of the population has true Celiac disease. Many more have what is know as gluten sensitivity What is the difference between the two, and how to know which one you have... read more. Is gluten the only substance in wheat people are sensitive to? ... read more.What are the ongoing Clinical Trials for Celiac Disease
There is still a lot that is not understood about how gluten's affect humans... many clinical trials are underway... read moreWhat are lectins -why are they toxic and cause illness?
Both plants and animals contain lectins. What are they and why can they be very toxic to our bodies. Why do beans have to be soaked and properly cooked? What is the role of lectins in autoimmune disease? ...read moreRole of Lectins in Inflammation
Although gluten has been in the limelight for sometime, many people may not realize that other lectins may be causing digestive issues... read more