Drugs for the Future:
the time many of today's students enter the workforce, career opportunities will
have radically changed. In April of 2003 the Human
Genome Project culminated in the completion of the full human genome. The
National Human Genome Research Institute now must move forward into the genomic
era with research aimed at improving human health and fighting disease.
molecular modeling scientists will be better able to design new and more potent
drugs against diseases such as Cancer, AIDS, and Arthritis.
to the Left: The 3D structure of a protein drug target. Using the crystallographic
structure fo a protein, Syrrx (a drug design company) used computational methods
to design a small molecule drug (shown in green) that can inhibit the disease-causing
activity of the protein.|
modeling not only has the potential to bring new drugs to the market, but a vast
array of new materials. The discovery of fullerenes, nanotubes...
view the BuckyTube in 3-D click here]
superconducting cuprates (as well as other complex inorganic compounds), are expected
to produce new materials in the optics, ceramic, semiconductor and biomaterials
5K Image In addition, recent structural determination
of vital photosynthetic proteins will lead the way to artificial photosynthesis.