| The Zone 
                  diet is a diet popularized 
                  in books by biochemist Barry 
                  Sears. It advocates balancing protein 
                  and carbohydrate 
                  in 3:4 ratios. It is not primarily a weight-loss "diet", though 
                  it can be used for that purpose. [1] 
                  Some nutritional experts, including some of Sears' former colleagues, 
                  are critical of his conclusions from the scientific evidence, 
                  contending that he has distorted or exaggerated the meaning 
                  of much of the basic research. They point out that no direct 
                  studies to verify his conclusions have been performed. Some 
                  experts consider The Zone a fad diet; others think it "not bad." 
                  [2] Theory The diet 
                  centers on a "40:30:30" ratio of calories obtained daily from 
                  carbohydrates, proteins, and fats, respectively. The exact formula 
                  is always under debate, but studies over the past several years 
                  (including a non-scientific study by the PBS documentary show 
                  Scientific American Frontiers) have shown that it can 
                  produce weight loss at reasonable rates. The Scientific American 
                  Frontiers study compared the effectiveness of several popular 
                  'diet' regimes including the Zone; somewhat to the surprise 
                  of the show's staff, the participants on the Zone experienced 
                  the greatest fat loss while simultaneously gaining muscle mass. 
                  Participants also reported the Zone as the easiest regime to 
                  adjust to, i.e. having the fewest adverse affects such as fatigue 
                  or hunger. Most people who report fatigue find that the fatigue 
                  diminishes by day 2 or 3. "The Zone" 
                  is Sears' term for proper hormone balance. When insulin levels 
                  are neither too high nor too low, and glucagon levels are not 
                  too high, then specific anti-inflammatory chemicals (types of 
                  eicosanoids) are released, which have similar effects to aspirin, 
                  but without downsides such as gastric bleeding. Sears claims 
                  that a 30:40 ratio of protein to carbohydrates triggers this 
                  effect, and this is called 'The Zone.' Sears claims that these 
                  natural anti-inflammatories are heart and health friendly. Additionally, 
                  the human body in caloric balance is more efficient and does 
                  not have to store excess calories as fat. 
                  The human body cannot store fat and burn fat at the same time, 
                  and Sears believes it takes time (significant time if insulin 
                  levels were high because of unbalanced eating) to switch from 
                  the former to the latter. Using stored fat for energy causes 
                  weight loss. Another 
                  key feature of the Zone diet, introduced in his later books, 
                  is an intake of the proper ratio of Omega-3 
                  to Omega-6 
                  fatty acids. Dr. Sears is believed to have popularized the taking 
                  of pharmaceutical grade Omega 3 fish oils.[3] Hormonal 
                  paradoxes Sears emphasizes 
                  a hormonal paradox contrary to the "low-fat" rationale, namely 
                  that low-fat diets increase the production of the hormone insulin, 
                  causing the body to store more fat. The example proposed by 
                  him is the cattle ranching practice 
                  of fattening livestock efficiently by feeding them lots of low-fat 
                  grain. He and others also point out the supposed irony that 
                  human diets in the West for the last twenty years have been 
                  full of low-fat carbohydrates, yet people are considered more 
                  obese now. Additionally, 
                  Sears suggests fat consumption as essential for "burning" 
                  fat. His rationale 
                  is: Monounsaturated fats in a meal contribute to a feeling of 
                  fullness and decreases the rate at which carbohydrates are absorbed 
                  into the bloodstream. Slower carbohydrate absorption means lower 
                  insulin levels which means less stored fat and a faster transition 
                  to fat burning. If the body needs energy and can't burn fat 
                  because of high insulin levels, a person feels tired as their 
                  brain starves and metabolism slows to compensate. This occurs 
                  because the brain runs on glucose 
                  and high insulin levels deplete blood glucose levels. Such condition, 
                  rebound hypoglycemia causes sweet cravings (which just starts 
                  the high-insulin cycle all over again). Sears describes 
                  a Zone meal as follows: "Eat as much protein as the palm of 
                  your hand, as much nonstarchy raw vegetables as you can stand 
                  for the vitamins, enough carbohydrates to maintain mental clarity 
                  because the brain runs on glucose, and enough monounsaturated 
                  oils to keep feelings of hunger away." Comparison 
                  to low-carb dietsThe Zone 
                  is considered a low-carb diet.[4] It is not as restrictive in total carbohydrate 
                  intake as some of the other low-carbohydrate diets (e.g. the 
                  Atkins diet) that became extremely popular throughout the United 
                  States in 2003 and 2004. Sears claims these other diets miss 
                  the point. According to him, they ignore the importance of hormonal 
                  balance, as well as the influence of dietary balance on digestion 
                  and hormone production. Specific 
                  cases  Italy The introduction 
                  of the Zone in Italy began in 1997 by a physician, Aronne Romano 
                  M.D. who applied this nutritional style to patients and athletes. 
                  Since the 2nd edition of the book "Come Raggiungere la Zona" 
                  (The Zone), in 1999, the Chef Memo Romano and his brother Aronne 
                  modified the original recipes and menu to suit the local food 
                  and habits. Famous 
                  obesity case Possibly 
                  the most famous case of someone using the diet effectively has 
                  been Mexican Manuel Uribe. After weighing in at around 560 kg 
                  (1234 lbs or over 88 stone) but within a year had lost about 
                  180 kg.[5].  Famous 
                  Followers Several 
                  Hollywood stars, including Jennifer Aniston, Renee Zellweger, 
                  Cindy Crawford, Charlie Sheen and Tiger Wood are believed to 
                  have followed the Zone diet. Criticism The American 
                  Heart Association does not recommend the Zone Diet due to high-protein, 
                  lack of essential nutrients, and little information on long-term 
                  effects.[6] However, characterization of the Zone 
                  diet as 'high-protein' may be inaccurate as the diet is not 
                  intended to increase protein intake beyond a typical American 
                  diet. Most Vegetarian 
                  or vegan diets, according to Sears, are as far as you can get 
                  from The Zone because they generally utilize very little protein 
                  relative to carbohydrate consumption. This, says Sears, prohibits 
                  the body from operating truly efficiently. As critical as Sears 
                  is of vegetarian and vegan diets, individuals who promote a 
                  vegetarian diet are also very critical of aspects of the Zone 
                  and similar diets. In 2000 Dr. Sears published the Soy zone 
                  where he outlined a zone diet based around soy protein, making 
                  it more vegetarian friendly. Other nutritional 
                  experts, including some of Sears' former colleagues, are critical 
                  of his conclusions from the scientific evidence, contending 
                  that he has distorted or exaggerated the meaning of much of 
                  the basic research. They point out that no direct studies to 
                  verify his conclusions have been performed.[7] Official 
                  Zone books (Partial 
                  list) 
                  Sears, 
                    Barry (1995). The Zone: A Dietary Road Map. HarperCollins 
                    Publishers.   
                    Sears's initial book on the Zone diet. 
                  Sears, 
                    Barry (1997). Mastering the Zone. HarperCollins Publishers.  
                    Sears urges substitution of raw vegetables for pastas, breads 
                    and refined sugars. More diagrams and flowcharts than in The 
                    Zone. 
                  Sears, 
                    Barry (1999). The Anti-Aging Zone. Regan Books. .  
                    Information on meditation, relaxation and exercise in addition 
                    to diet. 
                  Sears, 
                    Barry; Kotz, Deborah (2000). A Week in the Zone: A Quick 
                    Course in the Healthiest Diet for You. Regan Books. 
                  Sears, 
                    Barry (2000). The Soy Zone. Regan Books.  Discusses 
                    Sears preference for soy protein as part of his balanced eating 
                    program. "The longest-living people in the world" living in 
                    Okinawa, Japan consume much greater amounts of soy protein 
                    and eat smaller meals than most other people. 
                  Sears, 
                    Barry (2002). The Omega Rx Zone: The Miracle of the New 
                    High-Dose Fish Oil. Regan Books. 
                  Discusses 
                    "high-dose fish oil;" a newly introduced invented pharmaceutical 
                    grade fish oil that Sears touts as a medical miracle that 
                    will put the eicasonids in balance and reduce inflammation. 
                    Extra virgin olive oil is also promoted for its phytochemicals. 
                    
                  Sears, 
                    Barry (2005). The Anti-Inflammation Zone: Reversing the 
                    Silent Epidemic That's Destroying Our Health. Regan Books. 
                      References External 
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